The CLIB-Graduate Cluster Industrial Biotechnology is a joint initiative of three German universities: Heinrich-Heine-University Düsseldorf, Bielefeld University and TU Dortmund University.
In the frame of the programme, which is embedded into the Cluster Industrial Biotechnology CLIB2021, overall 84 PhD positions are offered to excellent candidates in the field of Industrial Biotechnology. Three PhD students were working at the laboratory of fluid separation processes in the field of downstream processing.
The separation of long chain isomers or mono- and diester is a special challenge as distillation is very elaborative because of the small separation factor and extraction processes do not match the high purity demands. In principal this separation task can be achieved by processes based on crystallization or liquid chromatography. For the design of these processes thermodynamic data is necessary, but this data cannot be measured as the branched molecules are not commercially available in the needed purity. Furthermore a lot of experiments are necessary to find an appropriate adsorption material for the liquid chromatography. The goal of this project is to develop the physical knowledge of a process model for the separation of long chain molecules with different architectures. To consider the influence of branching on thermodynamic phase behavior the Lattice Cluster Theory (LCT) is used to consider architectural influence of linear and branched molecules. This framework forms the basis for the modeling of crystallization of linear and branched molecules. The results are verified by selected experiments. The combination of the LCT with the density functional theory aims to the development of a method to predict adsorption isotherms of mixtures based on adsorptions isotherms of pure components. Further information can be found here.
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Location & approach
The campus of TU Dortmund University is located close to interstate junction Dortmund West, where the Sauerlandlinie A 45 (Frankfurt-Dortmund) crosses the Ruhrschnellweg B 1 / A 40. The best interstate exit to take from A 45 is “Dortmund-Eichlinghofen” (closer to South Campus), and from B 1 / A 40 “Dortmund-Dorstfeld” (closer to North Campus). Signs for the university are located at both exits. Also, there is a new exit before you pass over the B 1-bridge leading into Dortmund.
To get from North Campus to South Campus by car, there is the connection via Vogelpothsweg/Baroper Straße. We recommend you leave your car on one of the parking lots at North Campus and use the H-Bahn (suspended monorail system), which conveniently connects the two campuses.
TU Dortmund University has its own train station (“Dortmund Universität”). From there, suburban trains (S-Bahn) leave for Dortmund main station (“Dortmund Hauptbahnhof”) and Düsseldorf main station via the “Düsseldorf Airport Train Station” (take S-Bahn number 1, which leaves every 20 or 30 minutes). The university is easily reached from Bochum, Essen, Mülheim an der Ruhr and Duisburg.
You can also take the bus or subway train from Dortmund city to the university: From Dortmund main station, you can take any train bound for the Station “Stadtgarten”, usually lines U41, U45, U 47 and U49. At “Stadtgarten” you switch trains and get on line U42 towards “Hombruch”. Look out for the Station “An der Palmweide”. From the bus stop just across the road, busses bound for TU Dortmund University leave every ten minutes (445, 447 and 462). Another option is to take the subway routes U41, U45, U47 and U49 from Dortmund main station to the stop “Dortmund Kampstraße”. From there, take U43 or U44 to the stop “Dortmund Wittener Straße”. Switch to bus line 447 and get off at “Dortmund Universität S”.
The AirportExpress is a fast and convenient means of transport from Dortmund Airport (DTM) to Dortmund Central Station, taking you there in little more than 20 minutes. From Dortmund Central Station, you can continue to the university campus by interurban railway (S-Bahn). A larger range of international flight connections is offered at Düsseldorf Airport (DUS), which is about 60 kilometres away and can be directly reached by S-Bahn from the university station.
The H-Bahn is one of the hallmarks of TU Dortmund University. There are two stations on North Campus. One (“Dortmund Universität S”) is directly located at the suburban train stop, which connects the university directly with the city of Dortmund and the rest of the Ruhr Area. Also from this station, there are connections to the “Technologiepark” and (via South Campus) Eichlinghofen. The other station is located at the dining hall at North Campus and offers a direct connection to South Campus every five minutes.
The facilities of TU Dortmund University are spread over two campuses, the larger Campus North and the smaller Campus South. Additionally, some areas of the university are located in the adjacent “Technologiepark”.